Dr Svenja Pachernegg
Dr Svenja Pachernegg
Dr Svenja Pachernegg is a postdoctoral researcher in the Reproductive Development Group at the Murdoch Children's Research Institute in Melbourne. Svenja’s research interests are pluripotent stem cell biology, developmental biology, and disease modelling. She completed her PhD in Neuroscience in Germany in 2014, working on glutamate receptor function in mouse embryonic and neural stem cells. Svenja is now applying her stem cell and molecular biology skills to a differentiation protocol for human gonadal organoids to model Disorders of Sex Development.
Dr Svenja Pachernegg is a postdoctoral researcher in the Reproductive Development Group at the Murdoch Children's Research Institute in Melbourne. Svenja’s research interests are pluripotent stem cell biology, developmental biology, and disease...
Dr Svenja Pachernegg is a postdoctoral researcher in the Reproductive Development Group at the Murdoch Children's Research Institute in Melbourne. Svenja’s research interests are pluripotent stem cell biology, developmental biology, and disease modelling. She completed her PhD in Neuroscience in Germany in 2014, working on glutamate receptor function in mouse embryonic and neural stem cells. Svenja is now applying her stem cell and molecular biology skills to a differentiation protocol for human gonadal organoids to model Disorders of Sex Development.
Top Publications
- Pachernegg, S, Georges, E, Ayers, K. The Desert Hedgehog Signalling Pathway in Human Gonadal Development and Differences of Sex Development.. Sex Dev 16(2-3) : 98 -111 2022 view publication
- Li, M, Jancovski, N, Jafar-Nejad, P, Burbano, LE, Rollo, B, Richards, K, Drew, L, Sedo, A, Heighway, J, Pachernegg, S, et al. Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model.. J Clin Invest 131(23) : 2021 view publication
- Milligan, CJ, Pachernegg, S. Utilising Automated Electrophysiological Platforms in Epilepsy Research.. Methods Mol Biol 2188: 133 -155 2021 view publication
- Knarston, IM, Pachernegg, S, Robevska, G, Ghobrial, I, Er, PX, Georges, E, Takasato, M, Combes, AN, Jørgensen, A, Little, MH, et al. An In Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development.. Stem Cell Reports 15(6) : 1377 -1391 2020 view publication
- Mendis, GDC, Berecki, G, Morrisroe, E, Pachernegg, S, Li, M, Varney, M, Osborne, PB, Reid, CA, Halgamuge, S, Petrou, S. Discovering the pharmacodynamics of conolidine and cannabidiol using a cultured neuronal network based workflow.. Sci Rep 9(1) : 121 2019 view publication
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