A/Prof Silvia Velasco
A/Prof Silvia Velasco
Details
Role
Group Leader / Principal Research Fellow
Research area
Stem Cell Medicine
Group
Neural Stem Cells
Using pluripotent stem cell-derived 3D models of the human brain to study and identify new therapeutic approaches for neurological disorders.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Using pluripotent stem cell-derived 3D models of the human brain to study and identify new therapeutic approaches for neurological disorders.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by...
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by...
Using pluripotent stem cell-derived 3D models of the human brain to study and identify new therapeutic approaches for neurological disorders.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Top Publications
- Velasco, S, Kedaigle, AJ, Simmons, SK, Nash, A, Rocha, M, Quadrato, G, Paulsen, B, Nguyen, L, Adiconis, X, Regev, A, et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex.. Nature 570(7762) : 523 -527 2019 view publication
- Velasco, S, Paulsen, B, Arlotta, P. Highly reproducible human brain organoids recapitulate cerebral cortex cellular diversity.. 2019 view publication
- Pigoni, M, Uzquiano, A, Paulsen, B, Kedaigle, AJ, Yang, SM, Symvoulidis, P, Adiconis, X, Velasco, S, Sartore, R, Kim, K, et al. Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity. Human Molecular Genetics 32(18) : 2773 -2786 2023 view publication
- Velasco, S. Modeling brain disorders using transplanted organoids: Beyond the short circuit. Cell Stem Cell 29(12) : 1617 -1618 2022 view publication
- Pigoni, M, Uzquiano, A, Paulsen, B, Kedaigle, A, Yang, SM, Symvoulidis, P, Adiconis, X, Velasco, S, Sartore, R, Kim, K, et al. Cell-type specific developmental defects inPTEN-mutant cortical organoids converge on abnormal circuit activity. 2022 view publication
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