photo of Dr Natasha Tuano

Dr Natasha Tuano

Dr Natasha Tuano

Details

Role Senior Research Officer
Research area Stem Cell Medicine

Contact

Dr. Natasha Tuano is a Senior Research Officer working with A/Prof. Richard Mills on Duchenne muscular dystrophy by developing a non-viral CRISPR based therapy in collaboration with Prof. Niels Geijsen to restore Dystrophin expression using bioengineered skeletal muscle as a disease model, as part of the ReNEW program.

Natasha completed her Bachelor of Science with Honours at The University of Melbourne. Following on from her undergraduate studies, Natasha completed her PhD at Monash University under Prof. Assam El-Osta and Dr. Jun Okabe studying the role of a lysine methyltransferase, Set7 in stem cell derived smooth muscle cells and differentiation.

In 2017, Natasha was employed as a Research Fellow with A/Prof. Joseph (Sefi) Rosenbluh at Monash University in the Department of Biochemistry and Monash Biomedicine Discovery Institute. Natasha’s focus was to utilise pooled CRISPR technology for loss/gain of function screens to identify breast cancer risk genes.

Becoming a mother to a premature baby, Natasha took an interest in the vision and goals at Me&, a discovery stage biotechnology company involved in developing cell-based milk for preterm infants and worked as a Research Scientist II.
Dr. Natasha Tuano is a Senior Research Officer working with A/Prof. Richard Mills on Duchenne muscular dystrophy by developing a non-viral CRISPR based therapy in collaboration with Prof. Niels Geijsen to restore Dystrophin expression using...
Dr. Natasha Tuano is a Senior Research Officer working with A/Prof. Richard Mills on Duchenne muscular dystrophy by developing a non-viral CRISPR based therapy in collaboration with Prof. Niels Geijsen to restore Dystrophin expression using bioengineered skeletal muscle as a disease model, as part of the ReNEW program.

Natasha completed her Bachelor of Science with Honours at The University of Melbourne. Following on from her undergraduate studies, Natasha completed her PhD at Monash University under Prof. Assam El-Osta and Dr. Jun Okabe studying the role of a lysine methyltransferase, Set7 in stem cell derived smooth muscle cells and differentiation.

In 2017, Natasha was employed as a Research Fellow with A/Prof. Joseph (Sefi) Rosenbluh at Monash University in the Department of Biochemistry and Monash Biomedicine Discovery Institute. Natasha’s focus was to utilise pooled CRISPR technology for loss/gain of function screens to identify breast cancer risk genes.

Becoming a mother to a premature baby, Natasha took an interest in the vision and goals at Me&, a discovery stage biotechnology company involved in developing cell-based milk for preterm infants and worked as a Research Scientist II.

Top Publications

  • Karimnia, N, Rafehi, H, Tuano, NK, Ziemann, M, Harikrishnan, KN, Okabe, J, El-Osta, A. Current perspectives in Set7 mediated stem cell differentiation. Non-Coding RNA 2(4) : 14 2024
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  • Tuano, NK, Beesley, J, Manning, M, Shi, W, Perlaza-Jimenez, L, Malaver-Ortega, LF, Paynter, JM, Black, D, Civitarese, A, McCue, K, et al. CRISPR screens identify gene targets at breast cancer risk loci. Genome Biology 24(1) : 59 2024
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  • Davies, R, Liu, L, Taotao, S, Tuano, N, Chaturvedi, R, Huang, KK, Itman, C, Mandoli, A, Qamra, A, Hu, C, et al. CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies. Genome Biology 22(1) : 47 2021
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  • Beesley, J, Sivakumaran, H, Moradi Marjaneh, M, Lima, LG, Hillman, KM, Kaufmann, S, Tuano, N, Hussein, N, Ham, S, Mukhopadhyay, P, et al. Chromatin interactome mapping at 139 independent breast cancer risk signals. Genome Biology 21(1) : 8 2020
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  • Tuano, NK, Okabe, J, Ziemann, M, Cooper, ME, El-Osta, A. Set7 mediated interactions regulate transcriptional networks in embryonic stem cells. Nucleic Acids Research 44(19) : 9206 -9217 2016
    view publication

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