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Dr Maree Faux

Dr Maree Faux

Details

Role Senior Research Officer
Research area Stem Cell Medicine

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Dr Maree Faux is a biochemist and cancer cell biologist, a Senior Research Officer in the Neuro-oncology Group at Murdoch Children's Research Institute (MCRI) and an Honorary Research Fellow in the Department of Surgery, at the University of Melbourne.

Maree’s research aims to understand the biology and biochemical signalling pathways important in normal cell function and the molecular changes that contribute to cancer. Maree’s work has included the discovery of scaffolding complexes that anchor protein kinases and phosphatases to specific subcellular locations and understanding of how truncation of APC in colon tumours affects fundamental cellular processes. She is currently coordinating the developmental biology and cancer research activities in the Neuro-oncology Group. Her research aims to discover new transcriptional regulatory mechanisms and characterise these at the molecular and genomic level in normal development and in childhood cancer.

Over the course of her career, Maree has developed expertise in protein biochemistry and cancer cell biology and has made significant contributions to her field. She is passionate about research discovery and has continually pursued innovative ideas by developing and implementing new procedures to address research question. She is committed to nurturing talent and developing careers through mentoring and supervision of students and colleagues.
Dr Maree Faux is a biochemist and cancer cell biologist, a Senior Research Officer in the Neuro-oncology Group at Murdoch Children's Research Institute (MCRI) and an Honorary Research Fellow in the Department of Surgery, at the University of...
Dr Maree Faux is a biochemist and cancer cell biologist, a Senior Research Officer in the Neuro-oncology Group at Murdoch Children's Research Institute (MCRI) and an Honorary Research Fellow in the Department of Surgery, at the University of Melbourne.

Maree’s research aims to understand the biology and biochemical signalling pathways important in normal cell function and the molecular changes that contribute to cancer. Maree’s work has included the discovery of scaffolding complexes that anchor protein kinases and phosphatases to specific subcellular locations and understanding of how truncation of APC in colon tumours affects fundamental cellular processes. She is currently coordinating the developmental biology and cancer research activities in the Neuro-oncology Group. Her research aims to discover new transcriptional regulatory mechanisms and characterise these at the molecular and genomic level in normal development and in childhood cancer.

Over the course of her career, Maree has developed expertise in protein biochemistry and cancer cell biology and has made significant contributions to her field. She is passionate about research discovery and has continually pursued innovative ideas by developing and implementing new procedures to address research question. She is committed to nurturing talent and developing careers through mentoring and supervision of students and colleagues.

Top Publications

  • Frank, D, Bergamasco, M, Mlodzianoski, MJ, Kueh, A, Tsui, E, Hall, C, Kastrappis, G, Voss, AK, McLean, C, Faux, M, et al. Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth.. Elife 12: 2023
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  • Corona, SP, Walker, F, Weinstock, J, Lessene, G, Faux, M, Burgess, AW. Dual drug targeting to kill colon cancers.. Cancer Med 11(13) : 2612 -2626 2022
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  • Faux, MC, Weinstock, J, Gogos, S, Prato, E, Azimpour, AI, O'Keefe, R, Cathcart-King, Y, Garnham, AL, Ernst, M, Preaudet, A, et al. Combined Treatment with a WNT Inhibitor and the NSAID Sulindac Reduces Colon Adenoma Burden in Mice with Truncated APC.. Cancer Res Commun 2(2) : 66 -77 2022
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  • Leung, RF, George, AM, Roussel, EM, Faux, MC, Wigle, JT, Eisenstat, DD. Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes.. Front Neurosci 16: 843794 2022
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  • Hirokawa, Y, Clarke, J, Palmieri, M, Tan, T, Mouradov, D, Li, S, Lin, C, Li, F, Luo, H, Wu, K, et al. Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine.. Commun Biol 4(1) : 1067 2021
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