photo of Prof Ed Stanley

Prof Ed Stanley

Prof Ed Stanley

Details

Role Dep. Theme Director - Stem Cell Biology
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Ed Stanley is the Group Leader of the Immune Development Laboratory at the Murdoch Children’s Research Institute (MCRI). His laboratory uses human pluripotent stem cells to study human immunity and autoimmune diseases, such as type 1 diabetes. In a long standing collaboration with Professor Andrew Elefanty and Dr Elizabeth Ng (Blood Development Laboratory) at MCRI, Prof Stanley has contributed to the development of underpinning technologies relating to the use of human pluripotent stem cells as an experimental platform, encompassing the genetic modification of human pluripotent stem cell lines, differentiation platforms and cell culture medium formulations.

Following completion of his PhD in Molecular Biology at the University of Melbourne / Ludwig Institute, he worked on embryonic stem cells and haematopoietic development under the supervision of Professor Ashley Dunn, Ludwig Institute, Melbourne, Australia. He was awarded a C.J. Martin Fellowship to undertake postdoctoral training in the laboratory or Prof Peter Rigby at the National Institute of Medical Research in London, before retuning to Prof Richard Harvey’s group at the Walter and Eliza Hall Institute in Melbourne, where he worked on cardiogenesis and embryonic stem cells. Prof Stanley moved Monash University in 2002 to jointly head the Embryonic Stem Cell Differentiation Laboratory and build expertise in human embryonic stem cell genetic modification and differentiation. His laboratory relocated to the MCRI in 2012, where he has continued his long-standing collaboration with Prof Andrew Elefanty and Dr Elizabeth Ng, working on the haematopoietic, endocrine and immune development. Professor Stanley is currently deputy leader of the Stem Cell Biology Theme at MCRI and deputy director of Melbourne node of the reNEW Centre for Stem Cell Medicine supported by the Novo Nordisk Foundation.

Prof Ed Stanley holds active collaborations with:
• Dr Elizabeth Ng, Blood Development Laboratory, Murdoch Children's Research Institute
• Prof Andrew Elefanty, Blood Development Laboratory, Murdoch Children's Research Institute
• A/ Prof Stuart Mannering, Immunology Laboratory, St Vincent's Institute of Medical Research
• Prof Fergus Cameron, Endocrinology and Diabetes, The Royal Children's Hospital Melbourne
• A/Prof Dan Pellicci, Cellular Immunity Laboratory, Murdoch Children's Research Institute
• A/Prof Sarah Londrigan, Senior Lecturer Virology and Group Leader, Doherty Institute.
Professor Ed Stanley is the Group Leader of the Immune Development Laboratory at the Murdoch Children’s Research Institute (MCRI). His laboratory uses human pluripotent stem cells to study human immunity and autoimmune diseases, such as type 1...
Professor Ed Stanley is the Group Leader of the Immune Development Laboratory at the Murdoch Children’s Research Institute (MCRI). His laboratory uses human pluripotent stem cells to study human immunity and autoimmune diseases, such as type 1 diabetes. In a long standing collaboration with Professor Andrew Elefanty and Dr Elizabeth Ng (Blood Development Laboratory) at MCRI, Prof Stanley has contributed to the development of underpinning technologies relating to the use of human pluripotent stem cells as an experimental platform, encompassing the genetic modification of human pluripotent stem cell lines, differentiation platforms and cell culture medium formulations.

Following completion of his PhD in Molecular Biology at the University of Melbourne / Ludwig Institute, he worked on embryonic stem cells and haematopoietic development under the supervision of Professor Ashley Dunn, Ludwig Institute, Melbourne, Australia. He was awarded a C.J. Martin Fellowship to undertake postdoctoral training in the laboratory or Prof Peter Rigby at the National Institute of Medical Research in London, before retuning to Prof Richard Harvey’s group at the Walter and Eliza Hall Institute in Melbourne, where he worked on cardiogenesis and embryonic stem cells. Prof Stanley moved Monash University in 2002 to jointly head the Embryonic Stem Cell Differentiation Laboratory and build expertise in human embryonic stem cell genetic modification and differentiation. His laboratory relocated to the MCRI in 2012, where he has continued his long-standing collaboration with Prof Andrew Elefanty and Dr Elizabeth Ng, working on the haematopoietic, endocrine and immune development. Professor Stanley is currently deputy leader of the Stem Cell Biology Theme at MCRI and deputy director of Melbourne node of the reNEW Centre for Stem Cell Medicine supported by the Novo Nordisk Foundation.

Prof Ed Stanley holds active collaborations with:
• Dr Elizabeth Ng, Blood Development Laboratory, Murdoch Children's Research Institute
• Prof Andrew Elefanty, Blood Development Laboratory, Murdoch Children's Research Institute
• A/ Prof Stuart Mannering, Immunology Laboratory, St Vincent's Institute of Medical Research
• Prof Fergus Cameron, Endocrinology and Diabetes, The Royal Children's Hospital Melbourne
• A/Prof Dan Pellicci, Cellular Immunity Laboratory, Murdoch Children's Research Institute
• A/Prof Sarah Londrigan, Senior Lecturer Virology and Group Leader, Doherty Institute.

Top Publications

  • Arasaratnam, D, Bell, KM, Sim, CB, Koutsis, K, Anderson, DJ, Qian, EL, Stanley, EG, Elefanty, AG, Cheung, MM, Oshlack, A, et al. The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome. Scientific Reports 9(1) : 15928 2024
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  • Anderson, DJ, Kaplan, DI, Bell, KM, Koutsis, K, Haynes, JM, Mills, RJ, Phelan, DG, Qian, EL, Leitoguinho, AR, Arasaratnam, D, et al. NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. Nature Communications 9(1) : 1373 2024
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  • Richter, J, Stanley, EG, Ng, ES, Elefanty, AG, Traver, D, Willert, K. WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development. Genes 9(2) : 66 2024
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  • Lambshead, JW, Meagher, L, Goodwin, J, Labonne, T, Ng, E, Elefanty, A, Stanley, E, O’Brien, CM, Laslett, AL. Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces. Scientific Reports 8(1) : 701 2024
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  • Bellmaine, SF, Ovchinnikov, DA, Manallack, DT, Cuddy, CE, Elefanty, AG, Stanley, EG, Wolvetang, EJ, Williams, SJ, Pera, M. Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells. eLife 6: e24502 2024
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