photo of Dr Sara Howden

Dr Sara Howden

Dr Sara Howden

Details

Role Scientific Lead
Group iPSC Derivation & Gene Editing Facility

Top Publications

  • Houweling, PJ, Crossman, V, Tiong, CF, Coles, CA, Taylor, RL, Clayton, JS, Graham, A, Vlahos, K, Howden, SE, North, KN. Generation of a human ACTA1-tdTomato reporter iPSC line using CRISPR/Cas9 editing. Stem Cell Research 75: 103313 2024
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  • Hale, LJ, Howden, SE, Phipson, B, Lonsdale, A, Er, PX, Ghobrial, I, Hosawi, S, Wilson, S, Lawlor, KT, Khan, S, et al. 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening. Nature Communications 9(1) : 5167 2024
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  • Foltz, LP, Howden, SE, Thomson, JA, Clegg, DO. Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9. International Journal of Molecular Sciences 19(12) : 4127 2024
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  • Howden, SE, Wardan, H, Voullaire, L, McLenachan, S, Williamson, R, Ioannou, P, Vadolas, J. Chromatin-Binding Regions of EBNA1 Protein Facilitate the Enhanced Transfection of Epstein-Barr Virus-Based Vectors. Human Gene Therapy 060801084750033 2024
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  • Higgins, JW, Chambon, A, Bishard, K, Hartung, A, Arndt, D, Brugnano, J, Er, PX, Lawlor, KT, Vanslambrouck, JM, Wilson, S, et al. Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening. 2024
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